NCF2 antibody
Quick Overview for NCF2 antibody (ABIN7116849)
Target
See all NCF2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- NCF2 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- neutrophil cytosolic factor 2
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Isotype
- IgG
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Application Notes
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- NCF2 (Neutrophil Cytosolic Factor 2 (NCF2))
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Alternative Name
- NCF2
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Background
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Synonyms: Neutrophil cytosol factor 2 (NCF-2)|67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|Neutrophil NADPH oxidase factor 2|p67-phox|NCF2|NOXA2|P67PHOX
Background: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 68 kDa
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Gene ID
- 4688
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UniProt
- P19878
Target
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